Cancer stemness plays an important role in cancer initiation and progression, and constitutes an important cause of metabolic reprogramming, immune microenvironment remodeling and chemotherapy resistance. Non-coding RNAs (ncRNAs), including microRNAs (miRNAs), long non-coding RNAs (lncRNAs), and circular RNAs (circRNAs), have been proven to be involed in the cancer stemness. Here, we present ncStem database, which manually curated experimentally validated ncRNAs in cancer stemness. Users can retrieve detailed information about experimentally verified ncRNAs involved in the cancer stemness, including ncRNA name, ncRNA ID, disease, expression direction and so on. In addition, computationally predicted cancer stemness associated ncRNAs are also provided in ncStem. Furthermore, Function, Survival and Cell location tools are integrated in ncStem. Collectively, ncStem offers a user-friendly web server to search and predict ncRNAs in cancer stemness, which might facilitate research on cancer stemness and discover potential targets for cancer treatment.

Our Work

ncStem: A Comprehensive Resource of Curated and Predicted ncRNAs in Cancer Stemness.